What does endometrial disease mean?

Endometrial lesions refer to abnormal changes in the endometrium, including proliferative lesions, inflammatory lesions, tumor lesions, etc. Endometrial lesions may be related to endocrine disorders, infection, genetics and other factors, and usually manifest as abnormal uterine bleeding, menstrual disorders, lower abdominal pain and other symptoms. It is recommended to seek medical treatment promptly and follow the doctor's instructions for treatment after a clear diagnosis.

1. Proliferative lesions

Endometrial hyperplasia is the most common proliferative lesion and is mainly related to excessive estrogen levels. Long-term anovulation, polycystic ovary syndrome, obesity and other factors may lead to excessive endometrial hyperplasia. Patients may experience increased menstrual flow, prolonged periods, or irregular bleeding. Mild hyperplasia can be treated with progesterone capsules, dydrogesterone tablets and other drugs as directed by the doctor. Moderate to severe atypical hyperplasia may require hysteroscopic surgical removal.

2. Inflammatory lesions

Endometritis is an inflammatory disease, mostly caused by bacterial infection. Artificial abortion, uterine cavity operations, and sexually transmitted diseases are common causes. Patients may experience symptoms such as lower abdominal pain, fever, and abnormal vaginal discharge. In the acute stage, antibiotics such as ceftriaxone sodium for injection and metronidazole sodium chloride injection need to be used. Chronic inflammation can be treated with proprietary Chinese medicines such as Kangfu Xiaoyan Suppository.

3. Neoplasmic lesions

Endometrial polyps and endometrial cancer are neoplastic lesions. Polyps may be related to estrogen stimulation and manifest as intermenstrual bleeding ； Cancer is related to genetic mutations and long-term estrogen exposure, and postmenopausal bleeding is a typical symptom. Polyps can be treated by hysteroscopic polypectomy. Early-stage endometrial cancer requires total hysterectomy. Late-stage endometrial cancer may require chemotherapy drugs such as paclitaxel injection.

4. Atrophic lesions

Postmenopausal women may experience endometrial atrophy due to decreased estrogen levels. This physiological change usually does not require treatment, but if it is complicated by infection or bleeding, other pathologies need to be ruled out. Severe atrophy accompanied by repeated bleeding can be treated with topical estriol cream to improve symptoms, and close follow-up is required.

5. Iatrogenic lesions

Long-term use of anti-estrogen drugs such as tamoxifen may cause endometrial thickening or polyp formation. Patients receiving endocrine therapy for breast cancer need regular gynecological examinations and, if necessary, diagnostic dilation and curettage. If drug-related lesions occur, doctors will evaluate whether it is necessary to adjust the medication regimen or perform hysteroscopic surgical intervention.

Patients with endometrial lesions should keep their vulva clean and avoid unclean sex. Regular work and rest and weight control help regulate endocrine. Foods rich in phytoestrogens such as soy products and dark vegetables can be added to the diet in an appropriate amount, but not excessive. If abnormal bleeding occurs, you should seek medical treatment promptly and avoid taking hormonal drugs on your own. After surgery, patients need to follow the doctor's instructions for regular check-ups to monitor the condition of the endometrium.